What to Know about Antibody Production from Hybridoma Cells

by | Dec 1, 2022 | Business

When you need monoclonal antibodies to be produced, you should choose a company that has a process for antibody production from hybridoma cells. This allows them to assist clients with highly sensitive and specific monoclonal antibodies. They should have the capacity to produce high-purity monoclonal antibodies for any size client, whether they are needed for research or for large-scale commercial use.

Why Choose This Process?

Antibody production from hybridoma cells is one of the most desirable methods for producing monoclonal antibodies. You can use these antibodies for the treatment and research of many diseases, and they can be used for both therapeutic and diagnostic applications. High-purity monoclonal antibodies can be critical to the success of many different research efforts, and the design and production process is labor-intensive, time-consuming, and highly technical. When you work with a lab, they can manufacture your monoclonal antibodies using your own hybridoma cell line.

How the Process Works

Normally, hybridoma cell lines are created when mice are immunized with a specific antigen, and the B lymphocytes are obtained and isolated. Then the antibody-producing lymphocytes are fused with myeloma cell lines, resulting in the hybridoma cell lines. These cells are then cultured to produce custom monoclonal antibodies. A company that produces these cells can harvest antibodies from a continuous, concentrated stream of antibodies from a bioreactor, and they can scale it to expedite production for clients. When you need these monoclonal antibodies to be produced, you can rely on this type of company to do it for you.

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